Yildiz Laboratory: Mechanisms and Consequences of Biofilm Formation

Biofilms are aggregates of microbial communities composed of microorganisms and a matrix of extra-polymeric substances such as exopolysaccharides, proteins, and nucleic acids. Biofilms are prevalent and can have beneficial or detrimental consequences. We study biofilm formation in Vibrio cholerae, a bacterium responsible for the disease cholera. Biofilm formation enhances environmental survival and infectivity of the pathogen.

Our objectives are to 1) determine mechanisms underlying biofilm formation, 2) define regulatory networks controlling biofilm formation, 3) determine functions of biofilms and consequences of biofilm formation, 4) develop inhibitors to control biofilm formation.

Dr. Yildiz accepts graduate students from both the METX and PBSE graduate programs.

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